|
Symbol Name ID |
Kdm1a
lysine (K)-specific demethylase 1A MGI:1196256 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | hematopoietic system phenotype |
abnormal granulocyte differentiation |
abnormal monocyte differentiation |
increased hematopoietic stem cell proliferation |
enlarged spleen |
abnormal definitive hematopoiesis |
abnormal common myeloid progenitor cell morphology |
decreased common myeloid progenitor cell number |
abnormal erythropoiesis |
anemia |
abnormal bone marrow cell morphology/development |
decreased bone marrow cell number |
abnormal megakaryocyte morphology |
increased megakaryocyte cell number |
decreased erythroid progenitor cell number |
increased erythroid progenitor cell number |
abnormal megakaryocyte progenitor cell morphology |
increased basophil cell number |
increased eosinophil cell number |
abnormal proerythroblast morphology |
decreased fetal derived definitive erythrocyte cell number |
decreased erythrocyte cell number |
decreased neutrophil cell number |
decreased granulocyte number |
abnormal platelet morphology |
thrombocytopenia |
increased mean platelet volume |
decreased leukocyte cell number |
increased leukocyte cell number |
reticulocytopenia |
decreased hematopoietic stem cell number |
pancytopenia |
increased hematopoietic stem cell number |
small spleen |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||
| Gt(ROSA)26Sortm2(H1/tetO-RNAi:Kdm1a)Arte/Gt(ROSA)26Sor+ | * | ||||||||||||||||||||||||||||||||||
| Kdm1atm1(NCOM)Mfgc/Kdm1a+ | |||||||||||||||||||||||||||||||||||
| Kdm1atm1.1Sho/Kdm1atm1.1Sho Eportm1.1(EGFP/icre)Uk/Epor+ (conditional) |
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| Kdm1atm1.1Sho/Kdm1atm1.1Sho Commd10Tg(Vav1-icre)A2Kio/Commd10+ (conditional) |
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| Kdm1atm1.1Sho/Kdm1atm1.1Sho Tg(Mx1-cre)1Cgn/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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